Colchicine is an oral medication utilized for treating intense gout and familial Mediterranean fever (FMF). In intense gout there is extreme irritation because of the vicinity of uric corrosive precious stones that structure in hard joints. This reasons extreme agony, redness, and swelling of the influenced joint(s). Colchicine is valuable in smothering irritation brought about by gout. The accurate component of activity of colchicine is not known. It may include lessening in crystallization of uric corrosive prompting a decrease in the provocative reaction. Colchicine is not a pain relieving (agony executioner), yet it lessens ache brought on by gout.
Colchicine is utilized for the treatment of intense flares of gout. It likewise is utilized for treating FMF within grown-ups and kids 4 years old or more established. A few medications lessen the breakdown and disposal of colchicine from the body by diminishing the action of chemicals that breakdown colchicine. To dodge symptoms from colchicine the dosage of colchicine ought to be lessened when it is joined together with or utilized inside 14 days of medications that lessen its disposal.
Joining colchicine with statins, for instance atorvastatin (Lipitor), simvastatin (Zocor), and lovastatin (Mevacor), Lopid (gemfibrozil), or fenofibrate expands the danger of muscle related antagonistic impacts on the grounds that these medications additionally cause muscle related reactions.