Viralex Attack general information
What is Viralex Attack used for?
Viralex Attack capsules are a dietary supplement that contains a comprehensive formula of key ingredients used to provide immune support for optimal natural immune defence against infection. Viralex Attack capsules can be used to help prevent infection when at risk, such as when travelling in unhygienic places like planes; also to reduce the severity of infection. Viralex Attack capsules are also used to help reduce the severity of symptoms of infections like colds and flu and promote health and wellbeing. One of the key ingredients of Viralex Attack capsules acts rapidly and starts working within two hours so that they can be used to treat acute onset of symptoms.
How does Viralex Attack work?
Viralex Attack capsules contain an extract of the leaf of Andrographis paniculata a plant belonging to the Acanthaceae plant family and found found throughout China, India, Thailand, and Malaysia. Andrographis leaf extract has been widely used for medicinal purposes to treat a range of health issues1. Clinical studies suggest that Andrographis leaf extract may help reduce incidence and duration of symptoms of the common cold2, 3. Andrographolide is the main bioactive component of Andrographis leaf extract and has been found have immunomodulatory, anti-inflammatory and anti-microbial activity4, 5. Studies suggest that andrographolide reduce symptoms of HIV infection and uncomplicated upper respiratory tract infections including the common cold and sinusitis4. Studies carried out to determine the mechanism of action suggest that andrographolide has antiviral activity by inhibiting viral replication and also has anti-inflammatory activity by reducing the amount of inflammatory cytokines6. Viralex Attack capsules also contain a fermented extract of the yeast Saccharomyces cerevisiae marketed as EpiCor®. Clinical studies using this fermentate have indicated that EpiCor® provides immune support by modulating the immune response to reduce the incidence and severity of cold and flu-like symptoms7. The mechanism of action is thought to be by increasing the activity of Natural Killer cells (NK), which are a subset of lymphocytes (white blood cells) that recognise and destroy foreign cells in the body such as virus infected cells or cancer cells8. Secretory IgA (SIgA) is the most abundant class of antibodies found in the intestinal lumen. It is considered to be the first line of defence against invading pathogens and its production is stimulated by cytokines associated with the immune response9. In a study with healthy participants a significant increase in saliva SIgA was found in the group given EpiCor® compared with the placebo group, suggesting that EpiCor® supports mucosal immune defence10. EpiCor® was also shown have antioxidant properties, to reduce the inflammatory responses and may have beneficial effects on gut health8, 11. Olive oil is rich in monounsaturated fatty acids, mainly oleic acid, which has several known health benefits, including the low incidence of heart disease associated with the Mediterranean diet, in which olive oil is a major ingredient. Olive extract from both the fruit and the leaves of the Mediterranean olive Olea europaea also contains phenolic compounds like oleuropein, also a component of Viralex Attack capsules. Oleuropein has a wide range of pharmacological activities including antioxidant, anti-inflammatory, anti-atherogenic, anti-cancer, antimicrobial, antiviral, hypolipidemic and hypoglycemic12, 13, 14. Oleuropein has been shown to have antiviral activity against a range of viruses, including viral haemorrhagic septicaemia virus15, and HIV16. Several mechanisms of action have been proposed for the antiviral activity against HIV, including inhibiting entry of virus into the host cell and inhibition of its integration into the host DNA16. Olive leaf phenolic extract was also found to have antibacterial and antifungal activity by inhibiting microbial growth rate17. Zinc is a trace mineral and micronutrient, which means it is needed in only small amounts but has many important functions, including antioxidant and immunomodulatory activity. Zinc helps maintain immune function and promotes defence against bacterial infection18. Zinc deficiency causes increased risk of infection as a result of reduced antibody and cell mediated immune response due to compromised function of several immune cells, primarily T cells18, 19. Addition of zinc to Viralex Attack capsules helps promote a healthy immune system.
What does Viralex Attack contain?
Viralex Attack capsules contain the active ingredients Olea europaea (Olive) leaf extract (2700mg) (equivalent Oleuropein 60mg), Andrographis paniculata leaf extract 2000mg (equivalent Andrographolides 21mg). They also contain EpiCor®, (dried fermentate made using Saccharomyces cerevisiae 250mg) and Zinc (as Amino Acid Chelate 5mg)
Viralex Attack for Immune support
Viralex Attack capsules contain a comprehensive formula of active herbal ingredients, including Olea europaea (Olive) leaf extract and Andrographis paniculata leaf extract; also a dried yeast fermentate known as EpiCor®, which work together to boost the immune system and provide immune support for optimal natural immune defence against infection. Studies have shown that these ingredients have immunomodulatory, anti-inflammatory, anti-microbial and antioxidant activity and help reduce incidence and severity of symptoms of infection as well as reduce risk of infection. Viralex Attack capsules contain zinc, which is an important micronutrient with antioxidant and immunomodulatory activity. Zinc helps maintain immune function and promotes defence against bacterial infection. Viralex Attack capsules are used to maintain healthy functional immune cells, which helps reduce the severity of symptoms of infections like colds and flu and promotes health and wellbeing. One of the key ingredients of Viralex Attack capsules acts rapidly and starts working within two hours so that they can be used to treat acute onset of symptoms. Viralex Attack capsules can be used to help prevent infection when at risk, such as when travelling in unhygienic places like planes; also to reduce the severity of infection.
What are the side effects of Viralex Attack?
The most commonly reported side effects when taking Viralex Attack capsules include loss of appetite, diarrhoea, vomiting, nausea, rash, headache, and fatigue.
When should Viralex Attack not be used?
You should not use Viralex Attack capsules if you:
- are allergic to Oleuropein, Andrographis, EpiCor®, Zinc or any ingredients in Viralex Attack
- are pregnant or are breastfeeding
- have an auto-immune disease as andrographis might cause the immune system to become more active, and this could increase the symptoms
- have a bleeding disorders as andrographis might slow blood clotting, which might increase the risk of bleeding or bruising
- are taking medicines that interact with Viralex Attack, like immunosuppressant medication that decreases immune
How should Viralex Attack be taken?
You should take your Viralex Attack capsules swallowed whole with a glass of water and with food. You should take 2 capsules daily but this can increase to 3 capsules for an acute attack. You should continue to take your Viralex Attack capsules for as long as recommended by your health professional.
How long should you take Viralex Attack?
You should continue to take your Viralex Attack capsules for as long as recommended by your health professional.
Missed dose of Viralex Attack
If you miss a dose of Viralex Attack take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose.
How should Viralex Attack be stored?
You should store your Viralex Attack below 25°C in a cool dry place.
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- Cáceres DD, Hancke JL, Burgos RA, Wikman GK. Prevention of common colds with Andrographis paniculata dried extract. A Pilot double blind trial. Phytomedicine 1997 Jun;4(2):101-4. doi: 10.1016/S0944-7113(97)80051-7.
- Melchior J, Palm S, Wikman G. Controlled clinical study of standardized Andrographis paniculata extract in common cold – a pilot trial. Phytomedicine 1997 Feb;3(4):315-8. doi: 10.1016/S0944-7113(97)80002-5.
- Jayakumar T, Hsieh CY, Lee JJ, Sheu JR. Experimental and clinical pharmacology of andrographis paniculata and its major bioactive phytoconstituent andrographolide. Evid Based Complement Alternat Med 2013;2013:846740. doi: 10.1155/2013/846740. Epub 2013 Mar 24.
- Kumar RA, Sridevi K, Kumar NV, Nanduri S, Rajagopal S. Anticancer and immunostimulatory compounds from Andrographis paniculata. J Ethnopharmacol 2004 Jun;92(2-3):291-5.
- Cai W, Li Y, Chen S, Wang M, Zhang A, Zhou H, Chen H, Jin M. 14-Deoxy-11,12-dehydroandrographolide exerts anti-influenza A virus activity and inhibits replication of H5N1 virus by restraining nuclear export of viral ribonucleoprotein complexes. Antiviral Res 2015 Jun;118:82-92. doi: 10.1016/j.antiviral.2015.03.008. Epub 2015 Mar 20.
- Moyad MA, Robinson LE, Zawada ET, Kittelsrud J, Chen DG, Reeves SG, Weaver S. Immunogenic yeast-based fermentate for cold/flu-like symptoms in non-vaccinated individuals. J Altern Complement Med. 2010 Feb;16(2):213-8. doi: 10.1089/acm.2009.0310.
- Jensen GS, Redman KA, Benson KF, Carter SG, Mitzner MA, Reeves S, Robinson L. Antioxidant bioavailability and rapid immune-modulating effects after consumption of a single acute dose of a high- metabolite yeast immunogen: results of a placebo-controlled double-blinded crossover pilot study. J Med Food. 2011 Sep;14(9):1002-10. doi: 10.1089/jmf.2010.0174. Epub 2011 Apr 18.
- Mantis NJ, Rol N, Corthésy B. Secretory IgA’s complex roles in immunity and mucosal homeostasis in the gut. MucosalImmunology 2011: 4; 603-11
- Jensen GS, Patterson KM, Barnes J, Schauss AG, Beamand R, Reeves SG Robinson LE A Double-Blind Placebo-Controlled, Randomized Pilot Study: Consumption of a High-Metabolite Immunogen from Yeast Culture has Beneficial Effects on Erythrocyte Health and Mucosal Immune Protection in Healthy Subjects. The Open Nutrition Journal, 2008, 2, 68-75
- Jensen GS, Carter SG, Reeves SG, Robinson LE, Benson KF. Anti-inflammatory properties of a dried fermentate in vitro and in vivo. J Med Food. 2015 Mar;18(3):378-84. doi: 10.1089/jmf.2013.0158. Epub 2014 Aug 8.
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- Micol V, Caturla N, Pérez-Fons L, Más V, Pérez L, Estepa A. The olive leaf extract exhibits antiviral activity against viral haemorrhagic septicaemia rhabdovirus (VHSV). Antiviral Res. 2005 Jun;66(2-3):129-36. Epub 2005 Apr 18.
- Lee-Huang S, Huang PL, Zhang D, Lee JW, Bao J, Sun Y, Chang YT, Zhang J, Huang PL. Discovery of small-molecule HIV-1 fusion and integrase inhibitors oleuropein and Hydroxytyrosol: Part I. Integrase Inhibition. Biochem Biophys Res Commun. 2007; 354: 872–878.
- Pereira AP, Ferreira IC, Marcelino F, Valentão P, Andrade PB, Seabra R, Estevinho L, Bento A, Pereira JA. Phenolic compounds and antimicrobial activity of olive (Olea europaea L. Cv. Cobrançosa) leaves. Molecules. 2007 May 26;12(5):1153-62.
- Knoell DL, Liu MJ. Impact of zinc metabolism on innate immune function in the setting of sepsis. Int J Vitam Nutr Res. 2010 Oct;80(4-5):271-7.
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